L-Arginine, L-Citrulline & Nitric Oxide: What The Research Actually Shows

L-Arginine: the direct substrate

L-Arginine is the amino acid your body converts directly into nitric oxide via the enzyme nitric oxide synthase. Research on L-Arginine and blood flow is indexed on PubMed, generally at doses in the multiple grams per day range.

L-Citrulline: solving the absorption problem

Orally-consumed L-Arginine is heavily broken down in the gut and liver before reaching the bloodstream, a limitation called first-pass metabolism. L-Citrulline bypasses this, being absorbed intact and then converted into L-Arginine in the kidneys, which can raise blood arginine levels more effectively than L-Arginine itself. Research is indexed on PubMed.

Applying this to MemoHoney

L-Arginine, L-Arginine AKG, L-Citrulline HCL and L-Citrulline Malate together make up four of MemoHoney's six ingredients, all genuinely connected to nitric oxide production, though dose remains the unresolved question for this specific formula.